A Rare Case of 2,4-Dimethylamine Poisoning Managed with Forced Alkaline Diuresis

Abstract 2,4-dimethylamine (2,4-D) is a widely used herbicide with limited data on human toxicity. A 38-year-old male presented 2 h after ingesting around 100 mL of 58% 2,4-D salt. He had vomiting, altered sensorium, bradycardia, and respiratory distress. He received gastric lavage, intravenous fluids, atropine for bradycardia, and early forced alkaline diuresis initiated 6 h postingestion. Urinary pH was maintained between 7.8 and 8.2. The patient showed clinical improvement with resolution of bradycardia, rising urine output and improving renal function. He developed multilobar pneumonia on day 2 and was managed with antibiotics. He was discharged on day 7. Early forced alkaline diuresis may enhance elimination and prevent renal complications in 2,4-D poisoning.