Thermoreversible Hydrogel Containing Photoactivatable Tricarbonyl Mn(I) Terpyridine complexes for Therapeutic Carbon monoxide (CO) Release

Aakshika Sree M; Amilan Jose Devadoss

doi:10.1039/d5dt01527h

January 1, 2025Dalton Transactions

Thermoreversible Hydrogel Containing Photoactivatable Tricarbonyl Mn(I) Terpyridine complexes for Therapeutic Carbon monoxide (CO) Release

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Key Points

Controlled carbon monoxide release is achieved using a light-activated mechanism, enhancing its therapeutic application.
The addition of photoactivatable tricarbonyl Mn(I) complexes allows precise CO delivery, improving safety and efficacy.
This research utilizes thermoreversible hydrogels as carriers for CO-releasing molecules, facilitating targeted therapy.
These findings suggest potential advancements in using CO as a therapeutic agent in various medical applications.

Implication

Photoactivatable carbon monoxide-releasing molecules enhance targeted CO delivery, indicating potential therapeutic uses.

Abstract

Carbon monoxide (CO) is a well-established gasotransmitter known for its diverse physiological benefits. However, achieving controlled and targeted CO delivery remains challenging. To address this, light-activated carbon monoxide-releasing molecules (photoCORMs)...

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Cite This Study

M et al. (2025) studied this question.

synapsesocial.com/papers/68af5231ad7bf08b1eada796 https://doi.org/10.1039/d5dt01527h

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Thermoreversible Hydrogel Containing Photoactivatable Tricarbonyl Mn(I) Terpyridine complexes for Therapeutic Carbon monoxide (CO) Release

Key Points

Implication

Abstract

Discussion

Cite This Study

Thermoreversible Hydrogel Containing Photoactivatable Tricarbonyl Mn(I) Terpyridine complexes for Therapeutic Carbon monoxide (CO) Release

Key Points

Implication

Abstract

Discussion

Cite This Study

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