Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 22, 2025Open Access

Temperature-Induced Bifurcations and Timescale Warping in the Hodgkin-Huxley Model: Dynamical Systems Insights into Temperature Modulation of Neuronal Excitability and Action Potential Morphology

View Full Paper
Ask AI
Bookmark
Share

Authors

BHBrandon Jungwoo HanADArij Daou

Discussion

Loading...

Member takes

Overview

Dynamical systems analysis shows how temperature fluctuations impact neuronal excitability and action potential morphology.

Key Points

  • Increasing temperature leads to higher-frequency spikes but reduced amplitudes and loss of sustained firing.
  • Bifurcation analysis reveals critical boundaries indicating shifts to monostability in neuronal systems.
  • The Hodgkin-Huxley model highlights how different ion channel dynamics respond to temperature changes.
  • Temperature modulations significantly reshape the excitability landscape in biological neurons.

Cite This Study

Han et al. (2025) studied this question.

synapsesocial.com/papers/68af540fad7bf08b1eadb283https://doi.org/10.1101/2025.08.18.670807
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Temperature Induced Codimension-One and Codimension-Two Bifurcations in Hodgkin-Huxley Neurons2025
  2. 2Thermal effects and ephaptic entrainment in Hodgkin–Huxley model2024 · 5 citations
  3. 3Thermal effects and ephaptic entrainment in Hodgkin-Huxley model2024
  4. 4Dynamical mechanism of neuronal firing in the Hodgkin-Huxley model2025
  5. 5Neuronal excitability and parameter variability in the Hodgkin-Huxley model2026