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August 22, 2025Microbial GenomicsOpen Access

Epidemiological and phylogenetic characterization of human respiratory syncytial virus associated with severe acute respiratory infections in paediatric patients from 2016 to 2023 in Hangzhou, China

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Epidemiological trends and phylogenetic analysis revealed disruptions in HRSV patterns due to COVID-19 interventions.

Human respiratory syncytial virus genetic diversification was evident in pediatric severe acute respiratory infections.
Analysis included 2,277 samples and identified a novel viral lineage A.D.3.X with five unique substitutions.
Phylogenetic analysis revealed significant evolutionary changes coinciding with the COVID-19 pandemic years.
Study highlights the critical need for ongoing genomic surveillance to track HRSV evolution and inform prevention strategies.

Yu et al. (2025) studied this question.

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