Polymorphism and association of the BGN gene with cholesterol in lamb meat

Cholesterol levels in meat serve as an assessment for individuals selecting healthy meat options, correlating with an increased understanding of its importance to health. Biglycan (BGN) is hypothesized to influence cholesterol levels in lamb meat. This research aims to find variations of the BGN gene as potential genetic determinants of cholesterol levels in lambs. A total of 87 rams were analyzed for polymorphism using the PCR-RFLP method. The association between BGN gene polymorphisms and cholesterol in lamb meat was examined using a General Linear Model (GLM). This results from polymorphism by exhibiting two genotypes (GG and CC). A significant association (p < 0.05) was observed between BGN and cholesterol levels in lamb meat. Notably, rams with the GG genotype had significantly lower cholesterol levels when compared to those with the CC genotype. These results indicate that BGN is a good option for genetic selection to lower cholesterol levels in lambs.