Letter response discusses sinus rhythm's role in catheter ablation outcomes for persistent atrial fibrillation cases, suggesting significant implications.
Journal of Cardiovascular ElectrophysiologyEarly View REPLY Response to the Letter to the Editor Regarding "Temporary Restoration of Sinus Rhythm Improves Outcomes of Catheter Ablation for Longstanding Persistent Atrial Fibrillation" Mohamad Raad, Mohamad Raad orcid.org/0000-0002-5446-3786 Electrophysiology Section, Division of Cardiovascular Medicine, Perelman School of Medicine at University of Pennsylvania, Philadelphia, Pennsylvania, USASearch for more papers by this authorSanjay Dixit, Corresponding Author Sanjay Dixit [email protected] orcid.org/0000-0003-4292-8061 Electrophysiology Section, Division of Cardiovascular Medicine, Perelman School of Medicine at University of Pennsylvania, Philadelphia, Pennsylvania, USA Correspondence: Sanjay Dixit ([email protected])Search for more papers by this author Mohamad Raad, Mohamad Raad orcid.org/0000-0002-5446-3786 Electrophysiology Section, Division of Cardiovascular Medicine, Perelman School of Medicine at University of Pennsylvania, Philadelphia, Pennsylvania, USASearch for more papers by this authorSanjay Dixit, Corresponding Author Sanjay Dixit [email protected] orcid.org/0000-0003-4292-8061 Electrophysiology Section, Division of Cardiovascular Medicine, Perelman School of Medicine at University of Pennsylvania, Philadelphia, Pennsylvania, USA Correspondence: Sanjay Dixit ([email protected])Search for more papers by this author First published: 22 August 2025 https://doi.org/10.1111/jce.70048Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookxLinkedInRedditWechatBluesky No abstract is available for this article. References 1M. Raad, J. Oranefo, H. Yogasundaram, et al., "Temporary Restoration of Sinus Rhythm Improves Outcomes of Catheter Ablation for Longstanding Persistent Atrial Fibrillation," Journal of Cardiovascular Electrophysiology, First published, 23 June 2025, https://doi.org/10.1111/jce.16764. 10.1111/jce.16764 Web of Science® Google Scholar 2N. F. Marrouche, O. Wazni, C. McGann, et al., "Effect of MRI-Guided Fibrosis Ablation vs Conventional Catheter Ablation on Atrial Arrhythmia Recurrence in Patients With Persistent Atrial Fibrillation: The DECAAF II Randomized Clinical Trial," Journal of the American Medical Association 327, no. 23 (2022): 2296–2305, https://doi.org/10.1001/jama.2022.8579. 10.1001/jama.2022.8831 Web of Science® Google Scholar 3L. A. Eberly, A. Lin, J. Park, et al., "Presence of Sinus Rhythm at Time of Ablation in Patients With Persistent Atrial Fibrillation Undergoing Pulmonary Vein Isolation Is Associated With Improved Long-Term Arrhythmia Outcomes," Journal of Interventional Cardiac Electrophysiology 66, no. 6 (2023): 1455–1464, https://doi.org/10.1007/s10840-022-01441-4. 10.1007/s10840-022-01441-4 PubMed Web of Science® Google Scholar 4J. A. Clarnette, A. G. Brooks, R. Mahajan, et al., "Outcomes of Persistent and Long-Standing Persistent Atrial Fibrillation Ablation: A Systematic Review and Meta-Analysis," Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology 20, no. FI_3 (2018): f366–f376, https://doi.org/10.1093/europace/eux370. 10.1093/europace/eux370 Google Scholar 5H. T. Yu, J. Shim, and H. N. Pak, "Pulmonary Vein Isolation Alone Versus Additional Linear Ablation in Patients With Persistent Atrial Fibrillation Converted to Paroxysmal Type With Antiarrhythmic Drug Therapy: A Multicenter, Prospective, Randomized Study," Circulation: Arrhythmia and Electrophysiology 10, no. 6 (2017): e004915, https://doi.org/10.1161/CIRCEP.116.004915. 10.1161/CIRCEP.116.004915 PubMed Web of Science® Google Scholar 6R. S. Oakes, T. J. Badger, E. G. Kholmovski, et al., "Detection and Quantification of Left Atrial Structural Remodeling With Delayed-Enhancement Magnetic Resonance Imaging in Patients With Atrial Fibrillation," Circulation 119, no. 13 (2009): 1758–1767, https://doi.org/10.1161/CIRCULATIONAHA.108.811877. 10.1161/CIRCULATIONAHA.108.811877 PubMed Web of Science® Google Scholar 7R. R. Unni, R. T. Prager, R. Odabashian, et al., "Rhythm-Monitoring Strategy and Arrhythmia Recurrence in Atrial Fibrillation Ablation Trials: A Systematic Review," CJC Open 4, no. 5 (February 2022): 488–496, https://doi.org/10.1016/j.cjco.2022.02.001. 10.1016/j.cjco.2022.02.001 PubMed Web of Science® Google Scholar 8Z. H. Khan, Qura-tul-Ain, J. Amaranathan, and M. Khawar, "Critical Limitations of Temporary Sinus Rhythm Restoration in Enhancing Catheter Ablation Outcomes for Longstanding Persistent Atrial Fibrillation," Journal of Cardiovascular Electrophysiology, First published, 14 July 2025, https://doi.org/10.1111/jce.70012. 10.1111/jce.70012 Web of Science® Google Scholar Early ViewOnline Version of Record before inclusion in an issue ReferencesRelatedInformation
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