January 1, 2025Chemical Communications

Iridium-catalyzed [(5+1)-1] an-nulation of pyridinium 1,4-zwitterionic thiolates and sulfoxonium ylides: a ver-satile plat-form to in-dolizines

View Full Paper

Ask AI

Bookmark

The synthesis of indolizines was achieved through an efficient Iridium-catalyzed reaction pathway.
Key evidence shows the reaction efficiency, with a focus on a [(5+1)-1] annulation method using thiolates.
This was assessed using an Iridium (III)-catalyzed process alongside zwitterionic thiolates and sulfoxonium ylides.
Such findings may enable broader applications in synthetic organic chemistry, offering novel reaction pathways.

Implication

Demonstrates efficient synthesis of indolizines from thiolates and ylides, implying new pathways.

Abstract

An efficient synthesis of indolizines from pyridinium 1,4-zwitterionic thiolates and sulfoxonium ylides via a formal [(5+1)-1] pathway has been demonstrated. This reaction process involved an Iridium (III)-catalyzed (5+1) annulation, oxidation,...

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Fang et al. (2025) studied this question.

synapsesocial.com/papers/68af55d1ad7bf08b1eadc640 https://doi.org/10.1039/d5cc03199k

View Full Paper

Ask AI

Bookmark

Implication

Demonstrates efficient synthesis of indolizines from thiolates and ylides, implying new pathways.

Iridium-catalyzed [(5+1)-1] an-nulation of pyridinium 1,4-zwitterionic thiolates and sulfoxonium ylides: a ver-satile plat-form to in-dolizines

Key Points

Implication

Abstract

Discussion

Cite This Study

Iridium-catalyzed [(5+1)-1] an-nulation of pyridinium 1,4-zwitterionic thiolates and sulfoxonium ylides: a ver-satile plat-form to in-dolizines

Key Points

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading