What type of study is this?

This is a In Vitro Study study (also classified as: Animal Study).

August 19, 2025Open Access

Synthesis and Characterization of Copper Oxide (CuO) and Nickel Doped Copper Oxide Ni(CuO) Multifunctional Nanoparticles for Biological Applications

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The synthesis of copper oxide and nickel doped nanoparticles shows significant antibacterial activity and biocompatibility.

Copper oxide and nickel doped copper oxide nanoparticles exhibit notable antibacterial activity against multi-drug-resistant strains including Escherichia coli and Klebsiella.
The nanoparticles had an average size of 9.8 nm and showed low cytotoxicity with only 2 to 6 percent hemolysis at high concentrations.
Nickel doping improved the biocompatibility of the copper oxide nanoparticles and allowed for ROS generation in tumor cells.
This synthesis method illustrates potential applications in antimicrobial treatments and cancer therapies using multifunctional nanoparticles.

Khan et al. (2025) studied this question.

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