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August 18, 2025Open Access

Finding a Place for New Approach Methodologies (NAMs) in Biomedical Research

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Authors

ASAlexandra SchaffertAAArti AhluwaliaJBJeffrey J. Bajramovic̀

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Overview

Observational analysis highlights benefits of NAMs for improving human relevance in biomedical research, suggesting barriers must be overcome.

Key Points

  • New approach methodologies (NAMs) enhance the relevance of biomedical research, helping to replace animal experiments and improving investigation methods.
  • In areas like neuroscience, cardiovascular research, and oncology, NAMs provide tailored insights, increasing the potential for significant scientific advancement.
  • A proposed framework using clinical outcome pathways (COPs) facilitates the integration of diverse data derived from NAMs into experimental workflows.
  • Overcoming limitations in technology and education is essential for wider adoption of NAMs, enabling better collaboration and sustained investment.

Cite This Study

Schaffert et al. (2025) studied this question.

synapsesocial.com/papers/68af56f4ad7bf08b1eadce14https://doi.org/10.32388/l13yba
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