Case report of a 72-year-old man with a giant neck lipoma.

<ns3:p>Introduction: Lipomas (latin: lipoma) are the most common benign mesenchymal tumors, typically located subcutaneously and usually remaining small. In rare cases, giant lipomas (latin: lipoma gigantica) may develop, defined as those with a diameter exceeding 10 cm and weighing over 1,000 g. Giant lipomas in the head and neck region present a particular diagnostic and therapeutic challenge.Case Report: We present the case of a 72-year-old male Patient diagnosed with a giant neck tumor that had been slowly growing over many years. The tumor was non-tender on palpation, with the bulk of the mass located on the left side of the neck and extending posteriorly. The lesion was surgically excised in its entirety; the tumor measured 35 × 28 × 11 cm and weighed 2.70 kg. The postoperative course was uneventful. Histopathological examination confirmed the diagnosis of a lipoma with no signs of atypia. This case illustrates the successful surgical treatment of one of the largest giant lipomas of the neck reported in the literature to date.Discussion: The diagnosis of lipomas is based on clinical examination and medical imaging tests. Surgical excision remains the treatment of choice, especially for giant lipomas and/or those causing mechanical symptoms. Differential diagnosis is crucial to exclude liposarcoma, a malignant tumor requiring a different therapeutic approach. Recurrence is rare and typically results from incomplete resection. Postoperative follow-up is essential, particularly in cases of large or atypically presenting lesions.Conclusions: Giant lipomas of the neck are rare but may cause significant physical deformity and impair normal function. Accurate diagnosis, proper surgical planning, and histopathological evaluation are critical to achieving satisfactory therapeutic outcomes.</ns3:p>