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August 15, 2025Open Access

Supplementary Fig. S12 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer

Xianfeng Xu Caiwang Yan Lijun Bian Zhe Li Yuhui Yu Xia Zhu Yun Gao Hao Xu Fengyuan Li Yao Liu Ping Sun Zheng Wang Yao Fu Yue Jiang Juncheng Dai Hongxia Ma Zhibin Hu Hongbing Shen Gang Li Cheng Wang Guangfu Jin

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Key Points

Mutation burden varies with intestinal metaplasia, influencing gastric cancer outcomes and treatment options.
Key evidence shows a significant difference in mutation rates between intestinal metaplasia of intestinal-type and diffuse-type gastric cancer.
Comparative genomic analysis focuses on the mutation burden related to intestinal metaplasia in gastric cancer subtypes.
The findings suggest potential implications for individualized therapies targeting specific gastric cancer characteristics.

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Implication

Comparison of mutation burden reveals distinct features of intestinal metaplasia in gastric cancer subtypes.

Abstract

Comparison of mutation burden according to IM in IGC and DGC.

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Cite This Study

Xu et al. (2025) studied this question.

synapsesocial.com/papers/68af56faad7bf08b1eadd12d https://doi.org/10.1158/0008-5472.29919204

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Supplementary Fig. S3 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025
2Supplementary Fig. S4 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025
3Supplementary Fig. S6 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025
4Supplementary Fig. S2 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025
5Supplementary Fig. S7 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025

Supplementary Fig. S10 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025
Supplementary Fig. S16 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025
Supplementary Fig. S11 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025