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August 15, 2025Open Access

Supplementary Fig. S16 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer

Xianfeng Xu Caiwang Yan Lijun Bian Zhe Li Yuhui Yu Xia Zhu Yun Gao Hao Xu Fengyuan Li Yao Liu Ping Sun Zheng Wang Yao Fu Yue Jiang Juncheng Dai Hongxia Ma Zhibin Hu Hongbing Shen Gang Li Cheng Wang Guangfu Jin

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Key Points

Gastric cancer shows distinct genetic characteristics, providing insights into disease evolution.
The study reveals a notable dN/dS ratio in genes among intestinal metaplasia samples, indicating selection pressure.
Genomic analysis of tissues reveals changes in gene characteristics linked to gastric cancer progression.
These findings may enhance understanding of gastric cancer development and highlight potential therapeutic targets.

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Implication

Analysis uncovers evolving traits in gastric cancer and intestinal metaplasia, highlighting genetic selection.

Abstract

Estimated dN/dS ratio of positively selected genes in IM, IGC, and DGC samples.

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Cite This Study

Xu et al. (2025) studied this question.

synapsesocial.com/papers/68af56faad7bf08b1eadd209 https://doi.org/10.1158/0008-5472.29919192

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1Supplementary Fig. S12 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025
2Supplementary Fig. S10 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025
3Supplementary Fig. S11 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025
4Supplementary Fig. S3 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025
5Supplementary Fig. S2 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025

Supplementary Fig. S17 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025
Supplementary Fig. S4 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025
Supplementary Fig. S7 from Genomic Analyses Reveal the Evolving Characteristics of Intestinal Metaplasia and Gastric Cancer2025