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August 21, 2025PLoS ONEOpen Access

Epidemiology of liver cancer in Kazakhstan: data from the Unified National Electronic Health System, 2014–2023

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Authors

AAAyana AblayevaNazarbayev UniversityDSDmitriy SyssoyevNazarbayev UniversityRARuslan AkhmedullinNational Center for Biotechnology

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Implication

Data reveals rising liver cancer incidence and mortality in Kazakhstan, highlighting urgent public health needs.

Key Points

  • Liver cancer incidence rates have decreased slightly, but mortality rates have risen over the past decade.
  • Age-standardized incidence fell from 5.55 to 5.40 per 100,000, while mortality rose from 3.75 to 4.75 per 100,000.
  • Analysis utilized administrative data from a cohort of 10,455 liver cancer patients, applying Cox regression for risk assessment.
  • Findings underscore regional disparities in liver cancer burden, especially in West Kazakhstan and the need for targeted interventions.

Cite This Study

Ablayeva et al. (2025) studied this question.

synapsesocial.com/papers/68af56faad7bf08b1eadd2d6https://doi.org/10.1371/journal.pone.0330423
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