Biogenesis and implication of miRNAs in the development of diseases and their theranostic inhibitions

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This review highlights miRNAs as biomarkers in diseases, suggesting various novel delivery systems for therapeutic applications.

miRNAs play a critical role in gene expression regulation and their dysregulation is linked to disease progression.
The review emphasizes the application of miRNA mimics and anti-miRNAs as therapeutics to modulate miRNA expression.
Recent advances in miRNA-based delivery systems, including liposomal and exosomal methods, enhance therapeutic effectiveness.
Innovative strategies like DNA origami and selenium nanoparticles are explored for diagnosing and treating diseases.

Mandal et al. (2025) studied this question.

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