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August 22, 2025International Journal of Basic & Clinical PharmacologyOpen Access

Potential restorative effect of silymarin on liver histoarchitecture on paracetamol-induced in hepatotoxicity, in adult albino rats

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Authors

DNDavis Kiprono NgetichMaseno University MOM.W. OkothUniversity of Nairobi

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Implication

Observational analysis shows silymarin improves liver histoarchitecture in adult albino rats, suggesting a potential treatment against paracetamol toxicity.

Key Points

High dose of silymarin restores liver histoarchitecture due to paracetamol toxicity, enhancing hepatocyte distribution.
Results indicate a significant reduction in vacuolation of the central vein after treatment with silymarin.
The study involved 24 adult albino rats divided into control and treatment groups, utilizing standard micromorphological assessment.
These findings support silymarin as a promising therapeutic intervention for liver damage from paracetamol.

Cite This Study

Ngetich et al. (2025) studied this question.

synapsesocial.com/papers/68af570dad7bf08b1eaddc71 https://doi.org/10.18203/2319-2003.ijbcp20252560

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Implication

Observational analysis shows silymarin improves liver histoarchitecture in adult albino rats, suggesting a potential treatment against paracetamol toxicity.

Potential restorative effect of silymarin on liver histoarchitecture on paracetamol-induced in hepatotoxicity, in adult albino rats

Discussion

Member takes

Implication

Key Points

Cite This Study

Potential restorative effect of silymarin on liver histoarchitecture on paracetamol-induced in hepatotoxicity, in adult albino rats

Discussion

Member takes

Implication

Key Points

Cite This Study

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