This review reveals that non-pharmacological interventions improve symptoms in patients with neurodegenerative diseases, suggesting needed complementary care.
Neurodegenerative diseases like Alzheimer's disease, Parkinson's disease, and Huntington's disease are long-term conditions that slowly get worse over time. These illnesses affect the brain and nervous system, leading to serious problems with memory, thinking, movement, and behavior. Unfortunately, there is currently no cure for these diseases, and most available medications only help reduce symptoms rather than stop the disease from getting worse. Because of this, researchers and healthcare professionals have been exploring other ways to support patients. One growing area of interest is the use of non-pharmacological interventions—treatments that do not involve medications. Non-pharmacological interventions (NPIs) are being used more and more as complementary approaches to improve the daily lives of people living with neurodegenerative diseases. These approaches include things like physical exercise programs, brain training and therapy sessions, activities that stimulate the senses, and even changes in diet. Although they cannot cure these diseases, NPIs have shown promising results in helping people maintain their independence, reduce symptoms, and improve their overall well-being. This paper takes a closer look at the most promising non-drug treatments currently being studied. It will explore how each type of intervention works, the benefits they can offer, and how they can be added to regular care plans. By reviewing current scientific studies and real-world applications, this research aims to show how non-pharmacological strategies can make a meaningful difference in the lives of patients and their families.
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N.P.V. Nair (2025) studied this question.
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