Bis‐1,2,3‐Triazole Incorporated Organosilatrane for Dual Recognition of Cystine and Zr (IV): Exploring the Antioxidant Activity and Docking Study

A new bis‐1,2,3‐triazole associated silatrane 5 was synthesized and characterized by various analytical spectroscopic techniques such as FT‐IR, 1 H & 13 C‐NMR spectroscopy, and mass spectrometry. The probe 5 was employed for selective detection of cystine (Cys2) and Zr (IV) ion under spectrophotometric analysis. The LOD value for Cys2 was found to be 6.66 × 10 −6 M under UV–visible spectrophotometry and for Zr (IV) was 4.82 × 10 −7 M under fluorescence study. The stoichiometric ratio was found to be 1:1 for Cys2 and Zr (IV). The probe 5 has effectively scavenged DPPH, indicating that it possesses antioxidant properties. Using molecular docking, the binding energy against cystathionine protein was observed to be −6.24 kcal/mol. The above findings indicate that the probe 5 has potential applications in sensing as well as in biological fields.