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Platelet Function: Acute vs. Chronic Responses to Physical Exercise - A Review

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Acute exercise raises platelet reactivity, increasing thrombocytosis and hypercoagulability, particularly in untrained individuals.
Training lowers resting platelet reactivity and enhances endothelial nitric oxide bioavailability, promoting hemostatic balance.
Examining different exercise modalities, including aerobic and high-intensity training, reveals diverse impacts on platelet function.
Proper management is vital during extreme exercise in high-risk individuals to minimize thrombotic complications.

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This review uncovers how exercise modulates platelet function and hemostasis, suggesting varied effects across intensities.

Skouras et al. (2025) studied this question.

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