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July 31, 2025Journal of Biochemistry Microbiology and Biotechnology

Preliminary Bioactivity Profiling of Methanol Crude Extract from Clinacanthus nutans Leaves: Antioxidant, Antimicrobial, and Apoptotic Properties

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Authors

SNSyed Umar Faruq Syed NajmuddinRRRasidah Abdul RajakNANur Aina Aqilah Arlihamdi

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Overview

Extracted bioactive compounds from C. nutans show strong antioxidant and antimicrobial effects, suggesting therapeutic potential.

Key Points

  • C. nutans leaves exhibit strong antioxidant activity, with the 100% methanol extract showing an IC₅₀ of 1.13 mg/mL.
  • The highest total phenolic content was found in the 100% methanol extract, at 23.40 mg GAE/g.
  • Only the 60% and 70% extracts demonstrated notable antimicrobial activity, with a MIC of 10 mg/mL.
  • Apoptotic activity in CT26 cells was highest in the 100% extract, reaching 47.34%, indicating its potential as an anticancer agent.

Cite This Study

Najmuddin et al. (2025) studied this question.

synapsesocial.com/papers/68af59ddad7bf08b1eade9f8https://doi.org/10.54987/jobimb.v13i1.1085
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Also Consider

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  5. 5Evaluation of Antioxidant, Cytotoxic, and Anticancer Activities of Methanol Extract of <i>Annona reticulata</i> Linn. Leaves2025