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July 25, 2025Research Journal of Pharmaceutical Dosage Forms and Technology

A Review of Pulsatile Drug Delivery Systems

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Authors

MMManjusha P. MhaskeSSSwarup G. SalunkeAYAshok Yadav

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Overview

Review highlights advancements and challenges of pulsatile drug delivery systems, aiming to improve therapeutic outcomes.

Key Points

  • Pulsatile drug delivery systems enhance efficacy by releasing drugs at specific intervals, improving patient adherence.
  • These systems can significantly increase drug bioavailability and mitigate adverse reactions, supporting their clinical relevance.
  • Formulation technologies utilize hydrogels and pH-sensitive polymers to create effective pulsatile delivery profiles.
  • Challenges include manufacturing complexities and regulatory hurdles that must be overcome for clinical success.

Cite This Study

Mhaske et al. (2025) studied this question.

synapsesocial.com/papers/68af59e3ad7bf08b1eadeb50https://doi.org/10.52711/0975-4377.2025.00030
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1REVIEW ON PULSATILE DRUG DELIVERY SYSTEM2026
  2. 2Technological Aspects, Challenges and Applications of Pulsatile Drug Delivery System-A Critical Review2025
  3. 3A current era in pulsatile drug delivery system: Drug journey based on chronobiology2024 · 9 citations
  4. 4Review of Floating Pulsatile Drug Delivery Systems: Formulation, Evaluation, and Chronotherapeutic Applications2025
  5. 5Multi-pulse chronotherapeutic approaches for circadian rhythm disease management2025