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Case report details a retroperitoneal malignant peripheral nerve sheath tumor superinfected with Escherichia coli, emphasizing multidisciplinary management.
Case: We present the case of a 68-year-old woman with a right retroperitoneal malignant peripheral nerve sheath tumor (MPNST) complicated by an Escherichia coli urinary tract infection. Abdominal pain and leukocytosis led to the discovery of a hematogenous superinfection in the tumor's necrotic center. She underwent wide surgical resection and ertapenem antibiosis. No tumor recurrence was noted after 2 years. Conclusion: MPNSTs can present with superinfection in their necrotic core, complicating diagnosis and emphasizing the need for diligent, multidisciplinary management.
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Davis et al. (2025) studied this question.
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