Case report reveals severe pneumonitis after COVID-19 mRNA vaccination, highlighting cytokine response and recovery.
Coronavirus disease 2019 (COVID‐19) has resulted in global morbidity, mortality, and societal disruption. COVID‐19 mRNA vaccination was mandatory in many countries for a period; however, severe adverse events have been observed in some individuals who received the vaccine. We report a case of COVID‐19 mRNA vaccine‐induced pneumonitis in a male patient whose cytokine levels were analysed prior to admission. His serum IgE level was high (347 U/mL), and several cytokines were elevated: TNFα was 1.2 pg/mL, IL‐6 was 156 pg/mL, and IL‐8 was 75.0 pg/mL. The patient developed severe respiratory failure requiring ventilatory support but recovered after steroid pulse therapy.
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