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August 1, 2025JGH OpenOpen Access

Impacts of Ramadan Fasting on Metabolic and Hepatic Endpoints in Individuals With Metabolic Dysfunction‐Associated Fatty Liver Disease: A Systematic Review and Meta‐Analysis

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Authors

AKA B Kamrul-HasanHAHamid AshrafLNLakshmi Nagendra

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Overview

Systematic review shows fasting may improve metabolic and liver parameters in MAFLD patients, suggesting health benefits.

Key Points

  • Fasting during Ramadan is linked to significant reductions in liver enzymes, such as alanine transaminase and aspartate transaminase, improving liver health.
  • Weight loss occurred in fasting individuals, with an average decrease of 1.44 kg and reductions in body mass index and waist circumference reported during the fasting period.
  • Statistical analysis revealed fasting improved glycemic control, particularly reducing glycated hemoglobin levels by about 0.4% in those with metabolic dysfunction.
  • This assessment highlights the need for larger, more diverse studies to confirm these effects of Ramadan fasting on metabolic dysfunction and liver health.

Cite This Study

Kamrul-Hasan et al. (2025) studied this question.

synapsesocial.com/papers/68af5d63ad7bf08b1eae08ebhttps://doi.org/10.1002/jgh3.70264
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Beneficial effects of intermittent fasting: a narrative review2022 · 66 citations
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  3. 3The Effects of Ramadan Fasting on Body Composition, Blood Pressure, Glucose Metabolism, and Markers of Inflammation in NAFLD Patients: An Observational Trial2017 · 84 citations
  4. 4Effect of Ramadan fasting on alanine transferase (ALT) in nonalcoholic fatty liver disease (NAFLD)2017 · 8 citations
  5. 5Metabolic dysfunction: The silenced connection with fatty liver disease2023 · 40 citations