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Adaptation and Vulnerability in Chronic Pain: A Study of Profiles Based on Clinical and Psychological Factors

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This study identifies clinical profiles based on psychological factors and how they influence quality of life in chronic pain.

Two distinct clinical profiles emerged from the analysis of chronic pain participants, highlighting significant differences in psychological vulnerability and coping strategies.
Cluster 1 showed greater functional impairment and lower quality of life, with higher emotional distress compared to Cluster 2, which displayed better outcomes.
Using a two-step cluster analysis, psychological differences between the identified chronic pain profiles were assessed through independent samples t-tests.
These findings underscore the interplay between clinical and psychological factors in shaping the adaptation and experience of chronic pain.

Mora-Ascó et al. (2025) studied this question.

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