Case report identifies congenital ulcers in a neonate with LCH, suggesting the need for biopsy and monitoring.
Langerhans cell histiocytosis (LCH) is a neoplasm originating from immature haematopoietic myeloid precursor cells. It may uncommonly present with congenital ulcers. We report a case of a neonate admitted with a fever and a purulent congenital ulcer at the base of the neck, who, in the investigations, was diagnosed with LCH. This case highlights the importance of considering LCH in persistent, treatment-resistant cutaneous lesions in neonates and the necessity for biopsy and continuous monitoring.
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Abtahi‐Naeini et al. (2025) studied this question.
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