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August 1, 2025HLA

Identification of Four New HLA‐B*44 Alleles

Maria Loginova Nadezhda Morozova Igor Paramonov

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Key Points

Four new hla-b*44 alleles were characterized, enhancing our understanding of genetic variations in human leukocyte antigens.
The alleles include hla-b*44:431Q, hla-b*44:432Q, hla-b*44:433, and hla-b*44:434, broadening the classification of hla-b alleles.
Analysis employed next generation sequencing techniques to identify new alleles, a method known for high precision and efficiency.
Understanding these alleles may improve insights into immune responses and compatibility for organ transplants.

Implication

Investigation identifies four novel hla-b*44 alleles via next generation sequencing, indicating genetic diversity.

Abstract

Four new HLA‐B*44 alleles characterised by Next Generation Sequencing, HLA‐B*44:431Q, ‐B*44:432Q, ‐B*44:433 and ‐B*44:434.

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Cite This Study

Loginova et al. (2025) studied this question.

synapsesocial.com/papers/68af5f07ad7bf08b1eae1523 https://doi.org/10.1111/tan.70379

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