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This is a In Vitro Study study.

The Potential Antioxidant Mechanism of Essential Oils extracted from Cupressus sempervirens grown in Saudi Arabia

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The essential oils exhibit significant antioxidant activity, with an IC50 value of 0.352 mg/mL against DPPH.
GC-MS analysis identified α-pinene and δ-3-carene as major components, constituting 60.6% of the oils.
Molecular docking studies showed strong binding affinities of Germacrene-D, Cedrol, and Terpinen-4-ol to NADPH oxidase (2CDU).
These findings support the potential use of C. sempervirens essential oils as natural antioxidants in pharmaceuticals and cosmetics.

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Chemical analysis reveals antioxidant properties of essential oils in Cupressus sempervirens, suggesting potential in various industries.

Radhouane Chakroun (2025) studied this question.

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