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August 23, 2025Journal of Medical UltrasoundOpen Access

Utilizing an Agar/Silica Phantom for Magnetic Resonance Imaging-guided Focused Ultrasound Evaluation: Lesion Formation, Magnetic Resonance Imaging Manifestation, and Comparison with Porcine Tissue

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Authors

AAAnastasia AntoniouNENikolas EvripidouMGMarinos Giannakou

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Overview

Assessment shows improved lesion visibility in agar-based phantoms compared to porcine tissue, suggesting enhanced calibration for MRI-guided focused ultrasound.

Key Points

  • Lesion formation was achieved without significant shifting effects, and the agar/silica phantom provided excellent contrast on T2-weighted images.
  • The minimum focal temperature for measurable lesions was found to be 39°C, with lesion sizes increasing with energy levels applied during sonication.
  • An analysis of thermal profiling demonstrated good repeatability across different sonication protocols, confirming the phantom's reliability.
  • Agar-based phantoms can improve lesion visualization and calibration, making them valuable in preclinical evaluations of MRI-guided focused ultrasound.

Cite This Study

Antoniou et al. (2025) studied this question.

synapsesocial.com/papers/68af61fdad7bf08b1eae2804https://doi.org/10.4103/jmu.jmu-d-25-00008
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Also Consider

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  1. 1Magnetic Resonance Imaging Monitoring of Thermal Lesions Produced by Focused Ultrasound2024 · 1 citations
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  4. 4Magnetic resonance imaging‐guided large‐scale lesion patterning with high‐intensity focused ultrasound in homogeneous phantoms2026
  5. 5Estimation of the Proton Resonance Frequency Coefficient in Agar-based Phantoms2024