This review summarizes advancements in pH-responsive materials for tumor-targeted drug delivery, highlighting controlled release and design strategies.
Key Points
Efficient tumor-targeted drug delivery is achieved using pH-responsive materials, enhancing therapeutic efficacy and reducing toxicity.
The acidic nature of the tumor microenvironment allows for selective drug release from pH-responsive formulations like hydrogels and micelles.
The review systematically discusses multiple strategies for controlled release and theranostic integration in drug delivery systems.
Material design must consider the metabolic safety and controllable degradation to improve clinical applications of pH-responsive biomaterials.