A rare case of advanced primary peritoneal serous carcinoma: Diagnostic and therapeutic challenges of nonspecific symptoms

This case presents a 71-year-old woman with a history of hypertension and type 2 diabetes mellitus who developed vague gastrointestinal symptoms, including abdominal fullness, nausea, and significant weight loss. Through immunohistochemistry and imaging studies, she was diagnosed with advanced-stage primary peritoneal serous carcinoma (PPSC). She then underwent maximal debulking surgery, which confirmed stage IIIC PPSC with metastasis to the peritoneum, ovaries, and cervix. Her unique presentation emphasizes the critical need for heightened clinical suspicion in patients with atypical symptoms. The rarity of this diagnosis, especially at an advanced stage with nonspecific symptoms, underscores the challenge of early detection.