January 1, 2025Chemical ScienceOpen Access

Maleic anhydride derived diphosphines: adaptable chelators for receptor-targeted 99mTc, 64Cu and 188Re radiotracers

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Authors

RNRachel NuttallTechnical University of Munich IHIngebjorg HungnesKing's College London TPTruc Le-Buu PhamBiogen (United States)

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Implication

Observational analysis demonstrates maleic anhydride-derived diphosphines improve receptor-targeted imaging, indicating potential for better oncology diagnostics.

Key Points

The use of diphosphines significantly enhances receptor-targeted imaging with 99mTc, facilitating better diagnostic outcomes.
Key evidence shows these chelators can effectively bind multiple radionuclides, including 99mTc and 188Re, for imaging purposes.
This research utilizes maleic anhydride-derived compounds to explore their role as adaptable chelators for imaging.
The findings highlight the potential for these diphosphines to enable more accurate oncology imaging; broader applications remain to be explored.

Cite This Study

Nuttall et al. (2025) studied this question.

synapsesocial.com/papers/68af6203ad7bf08b1eae2b26 https://doi.org/10.1039/d5sc02110c

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Implication

Observational analysis demonstrates maleic anhydride-derived diphosphines improve receptor-targeted imaging, indicating potential for better oncology diagnostics.

Maleic anhydride derived diphosphines: adaptable chelators for receptor-targeted 99mTc, 64Cu and 188Re radiotracers

Discussion

Member takes

Implication

Key Points

Cite This Study

Maleic anhydride derived diphosphines: adaptable chelators for receptor-targeted 99mTc, 64Cu and 188Re radiotracers

Discussion

Member takes

Implication

Key Points

Cite This Study

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