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Successful Early Treatment of Anti‐N‐Methyl‐d‐Aspartate Receptor Encephalitis Associated With Small Cell Lung Cancer in an Elderly Male Patient: A Case Report

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Rapid improvement in neuropsychiatric symptoms was achieved with high-dose intravenous corticosteroids, leading to recovery.
CSF analysis confirmed the presence of anti-NMDA antibodies, linking the encephalitis to the underlying small cell lung cancer.
The case emphasizes the need for timely diagnosis of autoimmune encephalitis in elderly individuals with acute symptoms.
Early immunotherapy initiation may significantly improve outcomes for patients with paraneoplastic encephalitis.

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Case report details rapid symptom improvement in a patient with neuropsychiatric symptoms linked to SCLC, highlighting prompt immunotherapy.

Kamikawa et al. (2025) studied this question.

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Case report details rapid symptom improvement in a patient with neuropsychiatric symptoms linked to SCLC, highlighting prompt immunotherapy.