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Rare and Aggressive Disease: Urinary Bladder Leiomyosarcoma

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Case report highlights aggressive nature of bladder leiomyosarcoma, indicating need for tailored therapies.

The patient experienced significant disease progression despite initial chemotherapy and surgical intervention.
Histology confirmed high-grade leiomyosarcoma, with extensive necrosis noted during pathological examination.
Radical cystectomy was performed to address a locally invasive mass in the bladder, revealing advanced disease.
The case emphasizes urgent need for personalized treatment strategies in rare and aggressive malignancies like leiomyosarcoma.

Venclovas et al. (2025) studied this question.

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