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This is a Systematic Review study.

August 26, 2025CureusOpen Access

Stem Cell Therapy for Myocardial Infarction and Heart Failure: A Comprehensive Systematic Review and Critical Analysis

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Significant improvements in left ventricular ejection fraction were observed across 35 studies, highlighting the potential of stem cell therapy in heart repair.
Cell-based therapies showed promise in stimulating growth factors and angiogenesis, which are critical for cardiac repair and recovery.
A comprehensive search identified diverse methodologies and cell types, emphasizing the complexity of clinical reproducibility in heart treatments.
Challenges remain in engraftment rates and optimal dosing, necessitating further exploration of delivery techniques and cell differentiation strategies.

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Systematic review analyzes stem cell therapy effects on heart failure and myocardial infarction, suggesting potential for enhanced recovery.

Abouzid et al. (2025) studied this question.

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Systematic review analyzes stem cell therapy effects on heart failure and myocardial infarction, suggesting potential for enhanced recovery.