Protocol outlines imaging and quantitative analysis of dendritic spine features, highlighting their role in synaptic connectivity and plasticity.
Dendritic spines are key sites of excitatory synaptic signaling, and their morphology reflects changes in connectivity and plasticity. This protocol outlines imaging and quantitative analysis of spine features, including density, length, head diameter, and subtype classification, enabling detection of structural alterations across experimental conditions.
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Greathouse et al. (2025) studied this question.
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