Systematic review examines changes in renal biomarkers in marathon runners, suggesting insights for diagnosing acute kidney injury.
The objectives of this review are: to measure changes in renal biomarker levels before, immediately after, and 24 hours post-marathon; to identify promising biomarkers for the diagnosis of acute kidney injury; and to describe the temporal patterns of biomarker dynamics in relation to the marathon. Materials and Methods: Inclusion criteria: studies of marathon runners reporting AKI-related biomarkers. Search in the following databases: PubMed, EMBASE, Web of Science, LILACS. Collected data: study design, participant characteristics, and biomarker values (pre-, post-, and 24 h post-race). Meta-analysis using random effects model. Risk of bias assessment: the National Heart, Lung, and Blood Institute pre–post tool.
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Leucuța et al. (2025) studied this question.
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