Тhe Potential of Cellular Therapies in the Field of Nephorlogy

The incidence of kidney diseases has been increasing in the last decade due to extended lifespan, which is often related to polymorbidity. Many chronic conditions slowly and progressively impair the kidney function and lead to chronic kidney disease (CKD). This condition is associated with high morbidity and mortality, elevated costs for renal replacement therapy (RRT) and heavy psychosomatic burden. At the same time, therapeutic options are limited to prophylactic and renoprotective medications and measurements, which can slow progression but not to restore the impaired function of the organ. With the development of cellular therapies new perspectives arise on the horizon with promising potential - mesenchymal stem cells (MSCs) and induced pluripotent cells (iPSCs). Here we review the current possibility of both cell types slowing and reversing the CKD course and assess their cost implication.