Immunohistochemical study of matrix metalloproteinases 2 and 9 in the placenta of spontaneous miscarriage

Rafla Hassan; Mukhtar K. Haba

doi:10.12991/jrespharm.1766301

October 10, 2024Journal of Research in PharmacyOpen Access

Immunohistochemical study of matrix metalloproteinases 2 and 9 in the placenta of spontaneous miscarriage

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Key Points

MMP-2 and MMP-9 showed strong expression in the placenta of normally delivered women, unlike in miscarriage cases.
In first-trimester miscarriage, about 60% exhibited weak expression of MMP-2, highlighting abnormalities in expression.
Immunohistochemical analysis was performed on placental specimens from 90 women across normal and miscarriage groups.
The findings may suggest that altered MMP expression could be linked to miscarriage, warranting further investigation.

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Implication

Immunohistochemical analysis shows altered MMP-2 and MMP-9 levels in placenta of women with spontaneous miscarriage, suggesting roles in embryo implantation and placentation.

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Cite This Study

Hassan et al. (2024) studied this question.

synapsesocial.com/papers/68af6595ad7bf08b1eae5240 https://doi.org/10.12991/jrespharm.1766301

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Immunohistochemical study of matrix metalloproteinases 2 and 9 in the placenta of spontaneous miscarriage

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Immunohistochemical study of matrix metalloproteinases 2 and 9 in the placenta of spontaneous miscarriage

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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