A mini-review for cancer cell migration and cancer metastasis

This mini-review addresses the critical issue of cancer metastasis, a process that significantly contributes to cancer-related mortality. The study delves into the molecular and cellular mechanisms underpinning cancer cell migration and metastasis, focusing on recent advances and key factors involved in each step of metastatic progression. The research highlights the complexity of cell migration, comparing single-cell migration with collective cell migration and emphasizing their roles in developmental processes and disease progression. The study also provides a detailed analysis of the five key steps in cancer metastasis: infiltration, intravasation, survival in the circulatory system, extravasation, and colonization, elucidating the cellular and molecular events driving each step. Overall, the findings underscore the importance of understanding cell migration in cancer biology, offering insights into potential therapeutic targets and strategies to prevent tumor dissemination and enhance cancer treatment outcomes.