Clinical study shows that higher estrogen metabolites improve antioxidant defense in premenopausal women, suggesting a link to oxidative stress risk postmenopause.
Key Points
Higher estradiol levels in premenopausal women correspond to improved antioxidant enzyme activities and total antioxidant capacity.
Premenopausal women exhibited significantly higher superoxide dismutase, catalase, and glutathione peroxidase activities compared to postmenopausal women.
This cross-sectional study of seventy women assessed correlations between estrogen metabolites and antioxidant defense parameters.
Study highlights that reduced protective estrogens after menopause may elevate risks for oxidative stress-related pathologies.