Podophyllin Keratopathy – Refractive Change

Objective: A case report of “Podophyllin keratopathy and its impact on corneal refractive change” due to accidental corneal touch of PODOWART solution from a cutaneous wart-like lesion over the left cheek. Design: This study involves case report and interventional. Methods: The authors present a 50-year-old male with acute podophyllum keratopathy that developed over 36 h of accidental corneal touch of topical podophyllum (Podowart). It responded well with topical steroids and anticollagenase drugs. The case followed up with a series of corneal topography and refractive error evaluations. Various changes in the topography and refractive changes were discussed. Results: refractive change and mild corneal haze. Conclusions: Early intervention can prevent severe damage to the cornea and refractive change, after accidental touch of podophyllin. Podowart should not be used for periocular cutaneous lesions.