Observational analysis shows conversion of 2-chloroacethylphenothiazine to thiazole derivatives, suggesting new synthesis pathways.
The possibility of using 2-chloroacetylphenothiazine (1) for the synthesis of thiazole moieties has been studied. In addition, we have investigated the convertion of 1 to methyl phenothiazine-2-glyoxylate (5) and phenothiazine-2-glyoxaldehyde (7) by the action of SeO2/CH3OH and dimethylsulphoxide respectively.
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Zoorob et al. (1980) studied this question.
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