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September 5, 2025Minerva Anestesiologica

The effects of permissive hypercapnia on regional cerebral oxygen saturation and postoperative delirium in obese patients undergoing laparoscopic bariatric surgery: a randomized controlled trial

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Permissive hypercapnia improved regional cerebral oxygen saturation in obese patients undergoing surgery.
The study showed lower incidence of postoperative delirium at a target PaCO2 of 50 mmHg in the hypercapnia group.
Patients with permissive hypercapnia had significantly reduced S100β protein levels within three days post-surgery.
No significant differences were found in postoperative pulmonary complications between the two groups.

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Implication

Randomized trial demonstrates improved regional cerebral oxygen saturation and reduced delirium in obese patients, indicating the benefits of permissive hypercapnia.

Cite This Study

Li et al. (2025) studied this question.

synapsesocial.com/papers/68bb3a2b2b87ece8dc954836 https://doi.org/10.23736/s0375-9393.25.18934-7

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Implication

Randomized trial demonstrates improved regional cerebral oxygen saturation and reduced delirium in obese patients, indicating the benefits of permissive hypercapnia.

The effects of permissive hypercapnia on regional cerebral oxygen saturation and postoperative delirium in obese patients undergoing laparoscopic bariatric surgery: a randomized controlled trial

Key Points

Discussion

Implication

Cite This Study

The effects of permissive hypercapnia on regional cerebral oxygen saturation and postoperative delirium in obese patients undergoing laparoscopic bariatric surgery: a randomized controlled trial

Key Points

Discussion

Implication

Cite This Study

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