Experience in using full thickness resection of a section of the intestinal wall using the FTRD system in various parts of the gastrointestinal tract

Background. Endoscopic full thickness resection of gastrointestinal tract wall in case of epithelial and subepithelial neoplasms using the full thickness resection device (FTRD) system is a relatively new and effective treatment method in the presence of an increased risk of intraoperative complications. Objective. To evaluate the effectiveness and safety of the FTRD system for endoscopic full thickness resection of the gastrointestinal tract wall in epithelial and subepithelial neoplasms. Material and methods. From 2019 to 2024, 10 full thickness resections using the FTRD system were performed in Loginov Moscow Clinical Scientific Center in 9 patients. There were 4 men and 5 women. Indications for surgery were epithelial neoplasms of the colon in 7 cases, 1 intervention was performed for a submucosal neoplasm in the rectum and 2 were performed for epithelial neoplasms of the duodenum. In 7 patients, it was performed for recurrent neoplasms after previously performed mucosal resection, one of them required repeated full thickness resection due to incomplete removal of the tumor at the first stage. In 2 patients, primary intervention was performed to remove tumors in the area of the appendix and submucosal neoplasm of the rectum. Results. The technical success of the intervention and R0 resection was achieved in 9 cases. One patient required repeated full thickness resection for 3 months. There were no intraoperative complications. Bleeding from the site of duodenal resection was detected in 1 patient on the second day after surgery, it was treated by coagulation under local anesthesia (Clavien—Dindo IIIA). Conclusion. The technique of endoscopic full thickness resection of various parts of the wall of gastrointestinal tract using the FTRD system is an effective method for removing tumors with high risks of intraoperative complications when performing traditional endoscopic mucosal resection methods.