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September 5, 2025JAMA Network OpenOpen Access

Low Measles Seropositivity in Vaccinated Children

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Authors

HQHuy Quang QuachSJSara Pace JonesIJIype Joseph

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Overview

Cross-sectional study assessed measles seropositivity in vaccinated children, highlighting ongoing breakthrough infections in India.

Key Points

  • Significant measles immunity gaps exist despite high vaccine coverage, posing challenges to elimination efforts.
  • About 90.8% of children showed positive measles-specific IgG, indicating substantial immunity; however, gaps remain.
  • This cross-sectional study involved 684 vaccinated children and their mothers, analyzing antibody responses to measles.
  • Findings indicate a need to strengthen immunization programs to address suboptimal immune responses to measles vaccination.

Cite This Study

Quach et al. (2025) studied this question.

synapsesocial.com/papers/68bb3a352b87ece8dc954eb0https://doi.org/10.1001/jamanetworkopen.2025.29409
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