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September 5, 2025Acta NeurochirurgicaOpen Access

Impact of acute alcohol intoxication and alcohol dependence on outcomes after subarachnoid hemorrhage

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Authors

ITIsaac B. ThormanJohns Hopkins UniversityAJAhamindra JainWestchester Medical CenterEMElad MashiachRutgers, The State University of New Jersey

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Implication

Longitudinal study reveals acute alcohol intoxication reduces mortality in patients, indicating a complex relationship with alcohol dependence.

Key Points

  • Increased blood alcohol concentrations were associated with decreased 30-day mortality after subarachnoid hemorrhage.
  • Patients with alcohol use disorder had a higher hazard of mortality compared to those without substance use disorders.
  • Those with severe alcohol dependence exhibited an even greater hazard of mortality compared to mild/moderate users.
  • The study utilized Cox proportional hazard models and propensity score matching to analyze the data across a substantial patient population.

Cite This Study

Thorman et al. (2025) studied this question.

synapsesocial.com/papers/68bb3a492b87ece8dc9559f5https://doi.org/10.1007/s00701-025-06639-9
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Also Consider

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  1. 1Alcohol consumption as a risk factor for poor outcome after aneurysmal subarachnoid haemorrhage.1992 · 76 citations
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  3. 3Aneurysmal Subarachnoid Hemorrhage and Cardiac Related Fatality: Who Dies and Why?2023 · 5 citations
  4. 4Hemostatic Factors as Predictors of Ischemic Heart Disease and Stroke in the Edinburgh Artery Study1997 · 353 citations
  5. 5Comparison of DSM-5 Classifications of Alcohol Use Disorders With Those of DSM-IV, DSM-III-R, and ICD-10 in a General Population Sample in Sweden2015 · 35 citations