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September 5, 2025

“Evaluation of the Analgesic Potential of Alstonia Scholaris Extracts Using Eddy’s Hot Plate Method”

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Evaluation reveals the analgesic effects and antioxidant properties of Alstonia scholaris extracts, indicating potential therapeutic benefits.

The methanolic extract of Alstonia scholaris significantly increased reaction times in the hot plate test, indicating strong analgesic properties.
At 400 mg/kg, the extract exhibited a peak response of 31.92 seconds, comparable to pentazocine's 10 mg/kg dosage.
Phytochemical analysis showed high levels of phenolic and flavonoid content in the methanolic extract, suggesting strong antioxidant activity.
The DPPH assay confirmed antioxidant activity with an IC₅₀ of 48.73 µg/ml, showing less potency than ascorbic acid.

Roy et al. (2025) studied this question.

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Evaluation reveals the analgesic effects and antioxidant properties of Alstonia scholaris extracts, indicating potential therapeutic benefits.