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This is a Literature Review study.

September 5, 2025

Current Perspectives and Barriers in Pharmacovigilance: Implications for Pharmacy Practice

Key Points

Pharmacovigilance is essential for identifying and preventing adverse drug reactions in healthcare systems.
Barriers like under-reporting and inadequate training hinder effective pharmacovigilance implementation.
Pharmacists can improve drug safety through active engagement in reporting and patient counseling on medications.
Technological advancements, such as AI and electronic health records, present new opportunities for enhancing pharmacovigilance.

Abstract

Pharmacovigilance (PV) is critical for identifying, assessing, and preventing adverse drug reactions (ADRs), which significantly burden global healthcare systems. India’s Pharmacovigilance Programme of India (PvPI) serves as the primary mechanism for drug safety monitoring. Recent developments include the integration of electronic health records, artificial intelligence (AI) for signal detection, patient-reporting platforms, and social media surveillance. Nonetheless, persistent challenges such as under-reporting, inadequate training, resource limitations, and low awareness continue to impede optimal PV implementation 1– 3. Pharmacists, with their specialized knowledge, are uniquely positioned to improve PV through detection, reporting, and patient counseling. This review evaluates technological advancements, discusses pharmacists’ roles, identifies challenges, and proposes strategies for strengthening PV systems. Enhanced pharmacist engagement and technology adoption hold promise for improved medication safety and public confidence

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