A Review on Nanosponges

Nanosponge formulation is the ongoing research in drug delivery systems. Nanosponge is a solid, tiny sponge filled with various drug molecules in their cavities and are excellent drug delivery systems. They are biocompatible and versatile, with applications extending beyond pharmaceuticals to detoxification, chemical catalysis, and gas adsorption. They can improve the aqueous solubility and bioavailability of drugs as they can load water and lipid-soluble drug molecules and reduce their side effects, in various dosage forms for controlled drug delivery such as oral, parenteral, topical.They can also be employed as a biocatalyst carrier in drug delivery by developing drug delivery systems for enzymes, proteins, vaccines, and antibodies. The current review describes the methods of preparation of Nanosponges, types of Nanosponges, factors influencing their productionand evaluation tests.Their applications and ease of fabrication, scalability, and ability to protect encapsulated drugs from degradation, they hold great promise for next generation nanomedicine and multifunctional therapeutic delivery.