Exploratory study finds long-term immunogenicity and boostability of rabies PrEP in immunocompromised adults, implying potential for enhanced protection during immunosuppressive therapy.
Journal Article Accepted manuscript Long-term immunogenicity and boostability of rabies pre-exposure prophylaxis (PrEP) in immunocompromised adults who received PrEP prior to the start of immunosuppressive therapy: an exploratory study Get access Jenny L Schnyder, MD , Jenny L Schnyder, MD Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Validation, Visualization, Writing - original draft Centre of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Division of Internal Medicine, Amsterdam UMC, Location University of Amsterdam, the Netherlands https://orcid.org/0000-0002-2691-8130 Search for other works by this author on: Oxford Academic PubMed Google Scholar Kim Sinderen, MD , Kim Sinderen, MD Methodology, Writing - original draft, Writing - review & editing Centre of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Division of Internal Medicine, Amsterdam UMC, Location University of Amsterdam, the Netherlands Search for other works by this author on: Oxford Academic PubMed Google Scholar Nita Schipper-Boer , Nita Schipper-Boer Conceptualization, Investigation, Project administration, Resources, Software, Writing - review & editing Central Military Hospital, Utrecht, the Netherlands Search for other works by this author on: Oxford Academic PubMed Google Scholar Sanne Terryn, PhD , Sanne Terryn, PhD Resources, Writing - review & editing Sciensano, Brussels, Belgium https://orcid.org/0000-0002-5524-9984 Search for other works by this author on: Oxford Academic PubMed Google Scholar Inne Nauwelaers, PhD , Inne Nauwelaers, PhD Resources, Writing - review & editing Sciensano, Brussels, Belgium Search for other works by this author on: Oxford Academic PubMed Google Scholar Cornelis Stijnis, MD , Cornelis Stijnis, MD Project administration, Resources, Writing - review & editing Centre of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Division of Internal Medicine, Amsterdam UMC, Location University of Amsterdam, the Netherlands Search for other works by this author on: Oxford Academic PubMed Google Scholar Martin P Grobusch, FRCP , Martin P Grobusch, FRCP Resources, Supervision, Writing - review & editing Centre of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Division of Internal Medicine, Amsterdam UMC, Location University of Amsterdam, the Netherlands Search for other works by this author on: Oxford Academic PubMed Google Scholar Abraham Goorhuis, PhD Abraham Goorhuis, PhD Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing - original draft, Writing - review & editing Centre of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Division of Internal Medicine, Amsterdam UMC, Location University of Amsterdam, the Netherlands To whom correspondence should be addressed. Centre for Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Division of Internal Medicine, Amsterdam UMC, Location University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands. Email: [email protected] https://orcid.org/0000-0001-7423-6217 Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Travel Medicine, taaf085, https://doi.org/10.1093/jtm/taaf085 Published: 28 August 2025 Article history Received: 28 May 2025 Revision received: 04 August 2025 Accepted: 25 August 2025 Published: 28 August 2025
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